研究業績

  • Mitsuaki Kashiwagi and Yu Hayashi.
    “Life Without Dreams: Muscarinic Receptors Are Required to Regulate REM Sleep in Mice.”
    Cell Reports 24, 2211-2212 (2018).

  • Shinichi Miyazaki, Chih-Yao Liu, and Yu Hayashi.
    “Sleep in vertebrate and invertebrate animals, and insights into the function and evolution of sleep.”
    Neuroscience Research 118, 3-12 (2017).

  • Yu Hayashi and Shigeyoshi Itohara.
    “Cutting-edge approaches to unwrapping the mysteries of sleep.”
    Neuroscience Research 118, 1-2 (2017).

  • K Yasuda, Y Hayashi, T Yoshida, M Kashiwagi, N Nakagawa, T Michikawa, M Tanaka, R Ando, A Huang, T Hosoya, T J McHugh, M Kuwahara and S Itohara.
    "Schizophrenia-like phenotypes in mice with NMDA receptor ablation in intralaminar thalamic nucleus cells and gene therapy-based reversal in adults"
    Translational Psychiatry 7: e1047 (2017)

  • Yasuhiro Ogawa, Yoko Irukayama-Tomobe, Nobuyuki Murakoshi, Maiko Kiyama, Yui Ishikawa, Naoto Hosokawa, Hiromu Tominaga, Shuntaro Uchida, Saki Kimura, Mika Kanuka, Miho Morita, Michito Hamada, Satoru Takahashi, Yu Hayashi, Masashi Yanagisawa.
    "Peripherally administered orexin improves survival of mice with endotoxin shock"
    eLife 2016;5:e21055 (2016)

  • Mitsuaki Kashiwagi, Yu Hayashi.
    "The Function of REM Sleep: Implications from Transgenic Mouse Models"
    Brain Nerve 68(10):1205-1211 (2016)

  • Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, Takeshi Kanda, Makito Sato, Zhiqiang Wang, Jing Ma, Shin Nakane, Jun Tomita, Aya Ikkyu, Miyo Kakizaki, Noriko Hotta-Hirashima,Satomi Kanno, Haruna Komiya, Fuyuki Asano, Takato Honda, Staci J. Kim, Kanako Harano, Hiroki Muramoto, Toshiya Yonezawa, Seiya Mizuno, Shinichi Miyazaki, Linzi Connor, Vivek Kumar, Ikuo Miura, Tomohiro Suzuki, Atsushi Watanabe, Manabu Abe, Fumihiro Sugiyama, Satoru Takahashi, Kenji Sakimura, Yu Hayashi, Qinghua Liu, Kazuhiko Kume, Shigeharu Wakana, Joseph S. Takahashi, Masashi Yanagisawa,
    “Forward-genetics analysis of sleep in randomly mutagenized mice,”
    Nature 539, 378–383 (2016)

    ※以下のNews & Viewsでも紹介されました
    Derk-Jan Dijk & Raphaëlle Winsky-Sommerer “Neuroscience: Sleepy and dreamless mutant mice,”
    Nature 539, 364–365 (2016)

  • †Yu Hayashi, Mitsuaki Kashiwagi, Kosuke Yasuda, Reiko Ando, Mika Kanuka, Kazuya Sakai, †Shigeyoshi Itohara,
    († 責任著者),
    “Cells of a common developmental origin regulate REM/non-REM sleep and wakefulness in mice,”
    Science 350, 957-961 (2015)
    Abstract, Full Text, Full Text (PDF)
    ※以下のPerspectiveでも紹介されました
    Vladyslav V. Vyazovskiy "Mapping the birth of the sleep connectome," Science 350, 909-910 (2015)

  • †Yu Hayashi, Chih-Yao Liu,
    († 責任著者),
    “The evolution and function of sleep”,
    'Brain Evolution by Design' (Springer) in press

  • Ayumi Suzuki, L.-J. Lee, Yu Hayashi, L. Muglia, Shigeyoshi Itohara, Reha Erzurumlu, Takuji Iwasato,
    “Thalamic adenylyl cyclase 1 is required for barrel formation in the somatosensory cortex”,
    Neuroscience 290, 518-52(2015)

  • 林 悠、宮崎 慎一,
    “睡眠マネジメント―産業衛生・疾病との係わりから最新改善対策まで― “(NTS) 
    第2編、第1章、第8節 “睡眠と脳機能”, (2014)

  • Hiroyuki Arakawa, Ayumi Suzuki, Shuxin Zhao, Vassiliy Tsytsarev, Fu-Sun LO, Yu Hayashi, Shigeyoshi Itohara, Takuji Iwasato, and Reha Erzurumlu,
    “Thalamic NMDA receptor function is necessary for patterning of the thalamocortical somatosensory map and for sensorimotor behaviors”,
    J Neurosci 34, 12001-12014(2014)

  • 林 悠 脳科学辞典・トランスジェニック動物 DOI:10.14931/bsd.1689 (2013)

  • 林 悠, “ニューロン同士をつなぐ神経突起の除去か維持かの決定におけるWnt-Ror経路の役割”,
    実験医学 28, 78–81(2010)

  • Takaaki Hirotsu, Yu Hayashi, Ryo Iwata, Hirofumi Kunitomo, Eriko Kage-Nakadai, Takeo Kubo, Takeshi Ishihara, Yuichi Iino,
    “Behavioural assay for olfactory plasticity in C. elegans”,
    Protocol Networks, DOI:10.1038/nprot.2009.139(2009)

  • †Yu Hayashi, *Takaaki Hirotsu, *Ryo Iwata, Eriko Kage-Nakadai, Hirofumi Kunitomo, Takeshi Ishihara, Yuichi Iino, Takeo Kubo,
    († 責任著者, * 同等貢献),
    “A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans”,
    Nature Neuroscience 12, 981-987(2009)

  • *Eriko Kage, *Yu Hayashi, Hideaki Takeuchi, Takaaki Hirotsu, Hirofumi Kunitomo, Takao Inoue, Hiroyuki Arai, Yuichi Iino, Takeo Kubo,
    (* 同等貢献),
    “MBR-1, a novel helix-turn-helix transcription factor, is required for pruning excessive neurites in Caenorhabditis elegans”,
    Current Biology 15, 1554-1559(2005)